Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,441
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1,441
Tocris Bioscience™ BAY 1797
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Selective P2X4 antagonist
| Target | P2X4 |
|---|---|
| CAS | 2055602-83-8 |
| Chemical Name or Material | N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C20H17ClN2O4S |
1,442
Tocris Bioscience™ Silodosin
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Selective α1A adrenoceptor antagonist (Ki = 0.036 nM)
| CAS | 160970-54-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H32F3N3O4 |
| Formula Weight | 495.53 |
1,443
Tocris Bioscience™ Ruthenium Red
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CAS: 11103-72-3 Molecular Formula: Cl6H46N14O2Ru3
| CAS | 11103-72-3 |
|---|---|
| Molecular Formula | Cl6H46N14O2Ru3 |
1,444
Tocris Bioscience™ MK6-83
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TRPML channel activator
| CAS | 1062271-24-2 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | MK6-83 |
| Recommended Storage | Store at 4°C |
| Synonym | 5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide |
| Molecular Formula | C16H20N2O2S2 |
| Formula Weight | 336.47 |
1,445
Tocris Bioscience™ PQ 401
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CAS: 196868-63-0 Molecular Formula: C18H16ClN3O2
| CAS | 196868-63-0 |
|---|---|
| Molecular Formula | C18H16ClN3O2 |
1,446
Tocris Bioscience™ Naspm trihydrochloride
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CAS: 1049731-36-3 Molecular Formula: C22H37Cl3N4O
| CAS | 1049731-36-3 |
|---|---|
| Molecular Formula | C22H37Cl3N4O |
1,447
Tocris Bioscience™ PSB 1115
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CAS: 152529-79-8 Molecular Formula: C14H14N4O5S
| CAS | 152529-79-8 |
|---|---|
| Molecular Formula | C14H14N4O5S |
1,448
Tocris Bioscience™ Sacubitril calcium
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Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
| Target | Additional Synthetic Protease Inhibitors |
|---|---|
| CAS | 1369773-39-6 |
| Purity | >98% |
| Chemical Name or Material | Ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-[1,1′-biphenyl]-4-pentanoate hemicalcium salt |
| Recommended Storage | Store at -20°C |
| Synonym | AHU 377 |
| Molecular Formula | C24H28NO5.1/2Ca |
| Formula Weight | 430.52 |
1,449
Tocris Bioscience™ P-3FAX-Neu5Ac
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Sialic acid analog; sialyltransferase inhibitor
1,450
Tocris Bioscience™ (R)-(-)-Apomorphine hydrochloride
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CAS: 314-19-2 Molecular Formula: C17H18ClNO2
| CAS | 314-19-2 |
|---|---|
| Molecular Formula | C17H18ClNO2 |
1,451
Tocris Bioscience™ CGP 35348
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CAS: 123690-79-9 Molecular Formula: C8H20NO4P
| CAS | 123690-79-9 |
|---|---|
| Molecular Formula | C8H20NO4P |
1,452
Tocris Bioscience™ CZC 25146
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Potent LRRK2 inhibitor
| CAS | 1191911-26-8 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | Pale-purple |
| Solubility | Soluble to 100mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | CZC 25146 |
| Recommended Storage | Store at -20°C |
| Synonym | N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide |
| Molecular Formula | C22H25FN6O4S |
| Formula Weight | 488.54 |
1,453
Tocris Bioscience™ HEPES
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Multipurpose buffer
1,454
Tocris Bioscience™ JP 1302 dihydrochloride
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CAS: 1259314-65-2 Molecular Formula: C24H26Cl2N4
| CAS | 1259314-65-2 |
|---|---|
| Molecular Formula | C24H26Cl2N4 |
1,455
Tocris Bioscience™ α,β-Methyleneadenosine 5'-triphosphate trisodium salt
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CAS: 1343364-54-4 Molecular Formula: C11H15N5Na3O12P3
| CAS | 1343364-54-4 |
|---|---|
| Molecular Formula | C11H15N5Na3O12P3 |